Next Generation Probiotic 

Cultures
GB BIO SCIENCE is the company centered around the latest scientific-technological innovations and their profound effect on human health, well-being and quality of life.
Research
The portfolio we create is always a result of diligent analyses based on a well-documented studies in the field of biology and nutrition health.
Manufacturing
GB BIO SCIENCE is dedicated to bring forth effective probiotics with highest quality as a solution to the fast-growing need for natural and clean alternatives to strengthen immune system and other vital structures in the body.
Next generation
Probiotics?

Probiotic bacteria are non-pathogenic microorganisms that, when ingested in sufficient viable numbers, exert a positive influence on the host.
Some of the beneficial effects of probiotics include balancing of the gastro-intestinal (GI) tract microflora, improvement of immune response, production and improvement of the utilization of nutrients, decrease in the symptoms of lactose intolerance and allergies in susceptible individuals, reduction of the risk of cancer, alleviation of irritable bowel syndrome and inflammatory bowel diseases.

에 대한

프로바이오틱스
차세대 프로바이오틱스


차세대 프로바이오틱스를 위한 B2B 프로바이오틱스 개발자 .
PB 브랜드로 프로바이오틱스를 개발할 수 있습니다.
건강상의 이점
인간의 소화관은 
신체의 다른 부분에 비해 가장 많은 수의 박테리아와 가장 많은 종의 서식지입니다.
실제로 우리 장에는 우리 몸에 있는 인간 세포보다 더 많은 박테리아가 있습니다.
위장관 미생물총은 

병원체에 대한 직접적인 방어, 장 상피를 개발 및 유지하는 역할을 통해 유기체 방어 강화, 
항체 생성 유도, 음식에서 소화되지 않는 화합물 대사, 발달하는 면역 체계 훈련과 같은 몇 가지 주요 기능을 가지고 있습니다.
장내 미생물총의 구성은 연령, 식습관, 지리, 스트레스 요인 등과 같은 요인에 따라 달라집니다 

. 미생물총의 균형이 깨지면 다양한 질병이 발생할 수 있습니다.


Helicobacter pylori
Helicobacter pylori는 만성 위염, 위궤양, 십이지장궤양 환자의 위점막에서 분리한 그람음성균이다.
H. pylori 제균은 궤양 재발을 확실히 예방하며, 제균 요법은 이제 소화성 궤양 재발 예방에 표준이 되었습니다.
H. pylori의 70~90%에서 제균이 이루어지지만 경우에 따라 치료에 대한 내성이 발생하기도 한다.
프로바이오틱스로 표준 요법을 보완하면 H. pylori의 박멸률이 높아집니다.



설사
소아의 바이러스성 및 로타바이러스성 설사는 탈수와 영양실조로 이어질 수 있으며 어린 소아의 경우 생명을 위협할 수 있습니다.
Probiotics는 설사 공격을 단축하고 예방 도구로 사용할 수 있습니다.
항생제 치료의 부작용인 설사는 항생제 치료를 받는 환자의 상당 부분에 영향을 미칩니다.
항생제는 표적 병원성 미생물과 함께 "좋은" 박테리아를 죽입니다.
이것은 장내 미생물의 균형에 영향을 미치고 설사를 유발합니다.
이러한 불균형은 지속되어 더 많은 건강 문제를 일으킬 수 있습니다.



변비 변비
는 전체 인구의 14%를 차지하며 여성과 노인에서 더 많습니다.
변비에 대한 대부분의 비처방 약물은 그다지 효과적이지 않거나 불쾌한 부작용이 있습니다. 

프로바이오틱스는 장 통과 시간, 배변 빈도 및 배변 일관성을 개선합니다. ‌ ‌ ‌미생물총




건강한 장에서 미생물군과 숙주는 장 상피에 의해서만 분리되는데, 장 상피는 
박테리아가 몸에 들어오는 것을 막는 장벽 역할을 하고 장내 박테리아를 숙주 면역 체계의 공격으로부터 보호합니다.
 
인간 유기체가 제대로 기능하기 위해서는 소위 "좋은" 박테리아와 "나쁜" 박테리아 사이에 균형이 필요합니다.
 
"나쁜" 박테리아의 존재는 인체 건강에 유익합니다. 
유해한 박테리아가 질병을 유발하는 수준으로 성장할 수 없는
환경을 조성하여 더 공격적인 병원균에 의한 감염으로부터 신체를 보호합니다  . 그러나 다양한 질병 상태에서 장 상피의 장벽 기능이 손상될 수 있습니다.

 

따라서 독소, 전염증성 물질 및 병원균에 대해 투과성이 됩니다. 

이 과정은 패혈증과 같은 다양한 심각한 상태와 관련이 있습니다.
 
당사의 프로바이오틱스는 균형 잡힌 장내 마이크로바이옴을 촉진하여 

장 감염의 위험을 줄이고 일반적인 장 건강 문제를 완화하는 등 소화관에 유익한 효과를 줍니다.
 
면역 반응의 상당 부분은 위장관에 있으며 그곳의 미생물총은 중요한 역할을 합니다.
따라서 장내 미생물총 구성의 균형은 인체 건강에 직접적인 영향을 미칩니다.
 
점점 더 많은 연구에서 균형 잡히고 영양이 풍부한 장내 미생물이 여러 가지 방식으로 면역 체계를 돕는다는 사실이 밝혀졌습니다.
 
첫째, 유익한 박테리아는 장의 보호 상피와 점액층을 강하게 유지하는 데 도움을 주어 "새는" 장의 위험을 줄입니다.
 

둘째, 그들은 면역 반응을 지원하는  장 벽의 내벽에 의해 사이토카인과 항체의 분비를 자극합니다  .
면역 체계는 면역 체계의 세포에 영향을 줄 수 있는 대사 산물을 생산하는 장내 세균의 능력으로 인해 변경될 수도 있습니다.
 
예를 들어 짧은 사슬 지방산은 발효를 통해 일부 장내 세균에 의해 생성될 수 있습니다.
 
그들은 선천성 면역 세포 생산의 급격한 증가를 자극합니다.
 
이 세포는 감염 확산을 제한하려는 선천적 면역 체계의 일부입니다.
 
결과는 효율적이고 균형 잡힌 면역 체계입니다.
 
따라서 프로바이오틱스는 면역 체계의 조절을 지원할 수 

있으며 감기와 같은 과도한 염증 및 감염을 완화하고 알레르기 위험을 줄일 수 있습니다.
A B O U T

B2B Probiotics Developer

B2B Specialized to supply according to client's Needs.
Next Generation Probiotics
Lactobacillus rhamnosus,,Lactobacillus acidophilus,
Lactobacillus casei, Lactobacillus plantarum,
Lacto-bacillus reuteri, Lactobacillus bulgaricus,
Streptococcus thermophilus etc.


Next Generation Probiotic that has no equivalent
GB BIO SCIENCE is the company centered around the latest scientific-technological innovations 
and their profound effect on human health, well-being and quality of life.
We aim to deliver the transformative power of probiotics to the world 

by giving them decades of research and expertise in the probiotic strain selection, fermentation process and product formulation.
The portfolio we create is always a result of diligent analyses based on a well-documented studies 

in the field of biology and nutrition health.
Above all we are dedicated to bring forth effective probiotics with highest quality as a solution 

to the fast-growing need for natural and clean alternatives to strengthen immune system and other vital structures in the body.

Next Generation Probiotics
In order to exert their positive effect, the beneficial bacteria must reach the colon in relatively high viable cell concentrations. 
They must survive the transit through the stomach and the small intestines, 
where they are exposed to harsh conditions, such as low pH values and pepsin presence and high bile salt concentrations. 
Thus, the most important probiotic characteristic is the ability of surviving the harsh environment in the upper gastro-intestinal tract. 
Another key feature is the production of sufficient amount of cells during the cultivation process in the production facilities. 
Therefore, strains possessing high growth rates and capable of gaining high amount of biomass 
in a short period are more suitable for industrial production of probiotics and probiotic foods.

Health Benefits
The human digestive tract is a home to the largest number of bacteria and the greatest number of species compared to other areas of the body.
In fact, there are more bacteria in our gut than there are human cells in our body.
The gastrointestinal microflora has several key functions: directly defending against pathogens, 

fortifying the defense of our organism by its role in developing and maintaining the intestinal epithelium, 
inducing antibody production, metabolizing indigestible compounds in food, training the developing immune system.
The composition of the gut microbiota depends on factors like age, diet, geography, stress factors, etc. 

When the balance of the microflora is disturbed, various diseases can occur.


Our Services
‌PB, OEM, B2B
‌Our production process employs the latest advances in cultivation and lyophilisation technologies.
Every probiotic strain is produced by using optimised process parameters taking into account its individual requirements.
This allows us to achieve very high concentrations of active cells in our products, which remain viable for a long time even when stored at room temperature.


Bacterial concentrates

Bacterial concentrates consist of selected bacteria which have been grown under closely controlled conditions in a liquid medium and concentrated into a smaller volume.

The concentrate could be liquid or dry, and may vary in composition depending on the bacterial strains used

B2B supply with client's Needs.

Lactobacillus rhamnosus,
Lactobacillus acidophilus,
Lactobacillus casei,
Lactobacillus plantarum,
Lacto-bacillus reuteri,
Lactobacillus bulgaricus,
Streptococcus thermophilus  etc.

Starter Cultures

The starter cultures are microbiological cultures which are used in initiating fermentation in a variety of processes, including those for production of various fermented dairy products, such as cheese, yogurt, etc., and the production of other foods, such as bread, sausage, pickles and sauerkraut.

Private Label, OEM

GB BIO SCIENCE is one of the very few probiotic companies on the market which can offer you an in depth, end-to-end process when it comes to private label.
We support our customers with expertise every step of the way, still making sure they are in control of the final outcome.
Our team of professionals is able to provide information, ideas and solution to any kind of complex problems: from research and development of the most suitable probiotic strains for our client's needs, to how these cultures can be incorporated in the end product and afterwards manufactured and packed in variety of forms - liquids, sachets, capsules, tablets, etc.

Active ingredients (Bacterial concentrates)

 Lactobacillus acidophilus
Rebalance of intestinal microflora
Reduction of gastrointestinal discomfort
Restoration of a physiological gut barrier
Low pH and bile tolerance
Strong adhesion to the intestinal mucosa
Immunomodulation
Inhibition of Escherichia coli and coliforms isolated from infants, Listeria monocytogenes Salmonela sp., Klebsiella pneumonia, Staphylococcus aureus.
Contains over 10B CFU/g
Available as lactose free and vegan formulas
Lactobacillus gasseri
Rebalance of intestinal microflora
Reduction of gastrointestinal discomfort
Restoration of a physiological gut barrier
Low pH and bile tolerance
Strong adhesion to the intestinal mucosa
Immunomodulation
Contains over 10B CFU/g
Available as lactose free and vegan formulas
Lactobacillus delbrueckii subsp. bulgaricus
Rebalance of intestinal microflora
Strong adhesion to the intestinal mucosa
Reduction of gastro-intestinal discomfort
Low pH and bile tolerance
Inhibition of Klebsiella pneumoniae and of different coliforms isolated from infants, Escherichia coli O157:H7, Listeria monocytogenes, Staphylococcus aureus
Contains over 100B CFU/g
Available as lactose free and vegan formulass
Lactobacillus rhamnosus
Rebalance of intestinal microflora
Reduction of gastrointestinal discomfort
Restoration of a physiological gut barrier
Strong adhesion to the intestinal mucosa
Production of exopolysaccharides
Low pH and bile tolerance
Survives through the GI tract
Immunomodulation
Diarrhea
Rotaviral diarrhea
Gastroenteritis
Inhibition of Salmonella sp, Escherichia coli O157:H7 and other coliforms, Listeria monocytogenes, Candida albicans, Staphylococcus aureus
Contains over 100B CFU/g
Available as lactose free and vegan formulas
Lactobacillus plantarum
Rebalance of intestinal microflora
Reduction of gastro-intestinal discomfort
Restoration of a physiological gut barrier
Low pH and bile tolerance
Antioxidant activity
Survives through the GI tract
Immunomodulation
Diarrhea
Gastroenteritis
Inhibition of Escherichia coli, Listeria monocytogenes, Enterococcus sp., Klebsiella sp., Candida albicans
Contains over 100B CFU/g
Available as lactose free and vegan formulas
Lactobacillus reuteri
Rebalance of intestinal microflora
Reduction of gastrointestinal discomfort
Restoration of a physiological gut barrier
Strong adhesion to the intestinal mucosa
Low pH and bile tolerance
Survives through the GI tract
Immunomodulation
Diarrhea
Rotaviral diarrhea
Gastroenteritis
Inhibition of Salmonella sp, Escherichia coli O157:H7 and other coliforms, Listeria monocytogenes, Candida albicans, Staphylococcus aureus
Contains over 100B CFU/g
Available as lactose free and vegan formulas
Lactobacillus casei
Rebalance of intestinal microflora
Reduction of gastrointestinal discomfort
Restoration of a physiological gut barrier
Strong adhesion to the intestinal mucosa
Low pH and bile tolerance
Survives through the GI tract
Immunomodulation
Diarrhea
Rotaviral diarrhea
Gastroenteritis
Inhibition of Salmonella sp, Escherichia coli O157:H7 and other coliforms, Listeria monocytogenes, Candida albicans, Staphylococcus aureus
Contains over 100B CFU/g
Available as lactose free and vegan formulas
Bifidobacterium animalis subsp. lactis
Low pH and bile tolerance
Survives through the GI tract
Immunomodulation
Antioxidant activity
Reduced glutathione and superoxide dismutase production
Constipation
Cholesterol lowering
Contains over 100B CFU/g
Bifidobacterium bifidum
Bifidobacterium longum
Bifidobacterium infants
Low pH and bile tolerance
Survives through the GI tract
Immunomodulation
Cholesterol lowering
Constipation
Contains over 100B CFU/g

Starter cultures
Classic starter for Bulgarian yoghurt
The starter for production of Bulgarian yoghurt is a symbiotic combination of L. bulgaricus and S. thermophilus, which were isolated from home-made yoghurts. It ensures optimal fermentation of milk at home and supports the development of the typical taste, flavour and texture of this authentic Bulgarian product.
Starter for probiotic yoghurts
Starter for production of home-made probiotic yoghurt is a combination of specially selected strains of bacteria with proven probiotic properties, which have been naturally isolated from natural sources in Bulgaria and human isolates. The probiotic lactic acid micro-organisms support the functions of the gastrointestinal tract and stimulate the immune system, thus maintaining the human body healthy. Contains L. bulgaricus, S. thermophilus and L. rhamnosus.
Starter cultures for plant-based yoghurts
Starter cultures for sour droughts


Starter cultures

Classic starter for Bulgarian yoghurt
The starter for production of Bulgarian yoghurt is a symbiotic combination of L. bulgaricus and S. thermophilus, which were isolated from home-made yoghurts. It ensures optimal fermentation of milk at home and supports the development of the typical taste, flavour and texture of this authentic Bulgarian product.
Starter for probiotic yoghurts
Starter for production of home-made probiotic yoghurt is a combination of specially selected strains of bacteria with proven probiotic properties, which have been naturally isolated from natural sources in Bulgaria and human isolates. The probiotic lactic acid micro-organisms support the functions of the gastrointestinal tract and stimulate the immune system, thus maintaining the human body healthy. Contains L. bulgaricus, S. thermophilus and L. rhamnosus.
Starter cultures for plant-based yoghurts
Starter cultures for sour droughts

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