Cultures
GB BIO SCIENCE is the company centered around the latest scientific-technological innovations and their profound effect on human health, well-being and quality of life.
Research
The portfolio we create is always a result of diligent analyses based on a well-documented studies in the field of biology and nutrition health.
Manufacturing
GB BIO SCIENCE is dedicated to bring forth effective probiotics with highest quality as a solution to the fast-growing need for natural and clean alternatives to strengthen immune system and other vital structures in the body.
Next generation
Probiotics?
Probiotic bacteria are non-pathogenic microorganisms that, when ingested in sufficient viable numbers, exert a positive influence on the host.
Some of the beneficial effects of probiotics include balancing of the gastro-intestinal (GI) tract microflora, improvement of immune response, production and improvement of the utilization of nutrients, decrease in the symptoms of lactose intolerance and allergies in susceptible individuals, reduction of the risk of cancer, alleviation of irritable bowel syndrome and inflammatory bowel diseases.
B2B Probiotics Developer for you
Next Generation Probiotics.
We can develop your Probiotics with PB brand
Health Benefits
The human digestive tract is a home to the largest number of bacteria
and the greatest number of species compared to other areas of the body.
In fact, there are more bacteria in our gut than there are human cells in our body.
The gastrointestinal microflora has several key functions: directly defending against pathogens,
fortifying the defense of our organism by its role in developing and maintaining the intestinal epithelium,
inducing antibody production, metabolizing indigestible compounds in food, training the developing immune system.
The composition of the gut microbiota depends on factors like age, diet, geography, stress factors, etc.
When the balance of the microflora is disturbed, various diseases can occur.
Helicobacter pylori
Helicobacter pylori is a Gram-negative bacterium isolated from the gastric mucosa of patients with chronic gastritis, gastric and duodenal ulcers.
H. pylori eradication clearly prevents ulcer recurrence, and eradication therapy is now standard in the prevention of peptic ulcer recurrence.
H. pylori eradication is achieved in 70–90% of cases, but in some cases occurs resistance to the treatment.
The supplementation of the standard therapy with probiotics increases the eradication rates of H. pylori.
Diarrhea
Viral and rotavirus diarrhea in children can lead to dehydration and malnutrition, which in small children could be life threatening.
Probiotics shorten the diarrhea attacks and can be used as a prophylactic tool.
Diarrhea as a side-effect of antibiotic therapy, affects a significant portion patients treated with antibiotics.
Antibiotics kill the “good” bacteria along with the targeted pathogenic microbes.
This affects the balance of the gut microflora and leads to diarrhea.
Such imbalance can persist and cause further health problems.
Constipation
The incidence of constipation is 14% of the word population suffers from with higher numbers among women and the elderly.
Most non-prescription drugs for constipation are not very effective or have unpleasant side effects.
Probiotics improve gut transit time, stool frequency, and stool consistency.
Intestinal Microflora
In the healthy intestinal tract, the microflora and the host are separated only by the intestinal epithelium,
which serves as a barrier that prevents bacteria from entering the body and also protects the bacteria in the gut from attacks by the host immune system.
In order for the human organism to function properly, a balance is needed between the so-called “good” and “bad” bacteria.
The presence of “bad” bacteria is beneficial to the human health-
they protect the body from infections caused by more aggressive pathogens, by creating an environment
in which the harmful bacteria cannot grow to disease-causing levels.
However, in various disease states, the barrier function of the intestinal epithelium may be compromised.
Thus, it becomes permeable for toxins, pro-inflammatory substances and pathogens.
This process has been associated with a range of serious conditions, such as sepsis.
Our probiotics promote a well-balanced intestinal microbiome,
with beneficial effects on the digestive tract, such as reducing the risk of intestinal infection and provide relief of common intestinal health problems.
A large part of the immune response is located in the gastrointestinal tract and the microflora there has an important role in it.
Thus, the balance of the composition of the gut microflora directly affects human health.
An increasing number of studies have shown that a balanced and nourished intestinal microbiota assists the immune system in multiple ways.
Firstly, the beneficial bacteria assist in keeping the protective epithelial and mucus layer of the intestine strong, which decreases the risk of a “leaky” gut.
Secondly, they stimulate the secretion of cytokines and antibodies by the lining of the intestinal wall,
which support the immune response.
The immune system can also be altered due to the gut bacteria's ability to produce metabolites that can affect cells in the immune system.
For example short-chain fatty acids can be produced by some gut bacteria through fermentation.
They stimulate a rapid increase in the production of innate immune cells.
These cells are part of the innate immune system that try to limit the spread of infection.
The results are an efficient and balanced immune system.
Probiotics can thus support the regulation of the immune system,
and may alleviate excessive inflammations and infections, such as common colds, as well as decrease the risk for allergies.
B2B Specialized to supply according to client's Needs.
Next Generation Probiotics
Lactobacillus rhamnosus,,Lactobacillus acidophilus,
Lactobacillus casei, Lactobacillus plantarum,
Lacto-bacillus reuteri, Lactobacillus bulgaricus,
Streptococcus thermophilus etc.
Next Generation Probiotic that has no equivalent
GB BIO SCIENCE is the company centered around the latest scientific-technological innovations
and their profound effect on human health, well-being and quality of life.
We aim to deliver the transformative power of probiotics to the world
by giving them decades of research and expertise in the probiotic strain selection, fermentation process and product formulation.
The portfolio we create is always a result of diligent analyses based on a well-documented studies
in the field of biology and nutrition health.
Above all we are dedicated to bring forth effective probiotics with highest quality as a solution
to the fast-growing need for natural and clean alternatives to strengthen immune system and other vital structures in the body.
Next Generation Probiotics
In order to exert their positive effect, the beneficial bacteria must reach the colon in relatively high viable cell concentrations.
They must survive the transit through the stomach and the small intestines,
where they are exposed to harsh conditions, such as low pH values and pepsin presence and high bile salt concentrations.
Thus, the most important probiotic characteristic is the ability of surviving the harsh environment in the upper gastro-intestinal tract.
Another key feature is the production of sufficient amount of cells during the cultivation process in the production facilities.
Therefore, strains possessing high growth rates and capable of gaining high amount of biomass
in a short period are more suitable for industrial production of probiotics and probiotic foods.
Health Benefits
The human digestive tract is a home to the largest number of bacteria and the greatest number of species compared to other areas of the body.
In fact, there are more bacteria in our gut than there are human cells in our body.
The gastrointestinal microflora has several key functions: directly defending against pathogens,
fortifying the defense of our organism by its role in developing and maintaining the intestinal epithelium,
inducing antibody production, metabolizing indigestible compounds in food, training the developing immune system.
The composition of the gut microbiota depends on factors like age, diet, geography, stress factors, etc.
When the balance of the microflora is disturbed, various diseases can occur.
Bacterial concentrates consist of selected bacteria which have been grown under closely controlled conditions in a liquid medium and concentrated into a smaller volume.
The concentrate could be liquid or dry, and may vary in composition depending on the bacterial strains used
Lactobacillus rhamnosus,
Lactobacillus acidophilus,
Lactobacillus casei,
Lactobacillus plantarum,
Lacto-bacillus reuteri,
Lactobacillus bulgaricus,
Streptococcus thermophilus etc.
The starter cultures are microbiological cultures which are used in initiating fermentation in a variety of processes, including those for production of various fermented dairy products, such as cheese, yogurt, etc., and the production of other foods, such as bread, sausage, pickles and sauerkraut.
GB BIO SCIENCE is one of the very few probiotic companies on the market which can offer you an in depth, end-to-end process when it comes to private label.
We support our customers with expertise every step of the way, still making sure they are in control of the final outcome.
Our team of professionals is able to provide information, ideas and solution to any kind of complex problems: from research and development of the most suitable probiotic strains for our client's needs, to how these cultures can be incorporated in the end product and afterwards manufactured and packed in variety of forms - liquids, sachets, capsules, tablets, etc.
Lactobacillus acidophilus
Rebalance of intestinal microflora
Reduction of gastrointestinal discomfort
Restoration of a physiological gut barrier
Low pH and bile tolerance
Strong adhesion to the intestinal mucosa
Immunomodulation
Inhibition of Escherichia coli and coliforms isolated from infants, Listeria monocytogenes Salmonela sp., Klebsiella pneumonia, Staphylococcus aureus.
Contains over 10B CFU/g
Available as lactose free and vegan formulas
Lactobacillus gasseri
Rebalance of intestinal microflora
Reduction of gastrointestinal discomfort
Restoration of a physiological gut barrier
Low pH and bile tolerance
Strong adhesion to the intestinal mucosa
Immunomodulation
Contains over 10B CFU/g
Available as lactose free and vegan formulas
Lactobacillus delbrueckii subsp. bulgaricus
Rebalance of intestinal microflora
Strong adhesion to the intestinal mucosa
Reduction of gastro-intestinal discomfort
Low pH and bile tolerance
Inhibition of Klebsiella pneumoniae and of different coliforms isolated from infants, Escherichia coli O157:H7, Listeria monocytogenes, Staphylococcus aureus
Contains over 100B CFU/g
Available as lactose free and vegan formulass
Lactobacillus rhamnosus
Rebalance of intestinal microflora
Reduction of gastrointestinal discomfort
Restoration of a physiological gut barrier
Strong adhesion to the intestinal mucosa
Production of exopolysaccharides
Low pH and bile tolerance
Survives through the GI tract
Immunomodulation
Diarrhea
Rotaviral diarrhea
Gastroenteritis
Inhibition of Salmonella sp, Escherichia coli O157:H7 and other coliforms, Listeria monocytogenes, Candida albicans, Staphylococcus aureus
Contains over 100B CFU/g
Available as lactose free and vegan formulas
Lactobacillus plantarum
Rebalance of intestinal microflora
Reduction of gastro-intestinal discomfort
Restoration of a physiological gut barrier
Low pH and bile tolerance
Antioxidant activity
Survives through the GI tract
Immunomodulation
Diarrhea
Gastroenteritis
Inhibition of Escherichia coli, Listeria monocytogenes, Enterococcus sp., Klebsiella sp., Candida albicans
Contains over 100B CFU/g
Available as lactose free and vegan formulas
Lactobacillus reuteri
Rebalance of intestinal microflora
Reduction of gastrointestinal discomfort
Restoration of a physiological gut barrier
Strong adhesion to the intestinal mucosa
Low pH and bile tolerance
Survives through the GI tract
Immunomodulation
Diarrhea
Rotaviral diarrhea
Gastroenteritis
Inhibition of Salmonella sp, Escherichia coli O157:H7 and other coliforms, Listeria monocytogenes, Candida albicans, Staphylococcus aureus
Contains over 100B CFU/g
Available as lactose free and vegan formulas
Lactobacillus casei
Rebalance of intestinal microflora
Reduction of gastrointestinal discomfort
Restoration of a physiological gut barrier
Strong adhesion to the intestinal mucosa
Low pH and bile tolerance
Survives through the GI tract
Immunomodulation
Diarrhea
Rotaviral diarrhea
Gastroenteritis
Inhibition of Salmonella sp, Escherichia coli O157:H7 and other coliforms, Listeria monocytogenes, Candida albicans, Staphylococcus aureus
Contains over 100B CFU/g
Available as lactose free and vegan formulas
Bifidobacterium animalis subsp. lactis
Low pH and bile tolerance
Survives through the GI tract
Immunomodulation
Antioxidant activity
Reduced glutathione and superoxide dismutase production
Constipation
Cholesterol lowering
Contains over 100B CFU/g
Bifidobacterium bifidum
Bifidobacterium longum
Bifidobacterium infants
Low pH and bile tolerance
Survives through the GI tract
Immunomodulation
Cholesterol lowering
Constipation
Contains over 100B CFU/g
Starter cultures
Classic starter for Bulgarian yoghurt
The starter for production of Bulgarian yoghurt is a symbiotic combination of L. bulgaricus and S. thermophilus, which were isolated from home-made yoghurts. It ensures optimal fermentation of milk at home and supports the development of the typical taste, flavour and texture of this authentic Bulgarian product.
Starter for probiotic yoghurts
Starter for production of home-made probiotic yoghurt is a combination of specially selected strains of bacteria with proven probiotic properties, which have been naturally isolated from natural sources in Bulgaria and human isolates. The probiotic lactic acid micro-organisms support the functions of the gastrointestinal tract and stimulate the immune system, thus maintaining the human body healthy. Contains L. bulgaricus, S. thermophilus and L. rhamnosus.
Starter cultures for plant-based yoghurts
Starter cultures for sour droughts
Classic starter for Bulgarian yoghurt
The starter for production of Bulgarian yoghurt is a symbiotic combination of L. bulgaricus and S. thermophilus, which were isolated from home-made yoghurts. It ensures optimal fermentation of milk at home and supports the development of the typical taste, flavour and texture of this authentic Bulgarian product.
Starter for probiotic yoghurts
Starter for production of home-made probiotic yoghurt is a combination of specially selected strains of bacteria with proven probiotic properties, which have been naturally isolated from natural sources in Bulgaria and human isolates. The probiotic lactic acid micro-organisms support the functions of the gastrointestinal tract and stimulate the immune system, thus maintaining the human body healthy. Contains L. bulgaricus, S. thermophilus and L. rhamnosus.
Starter cultures for plant-based yoghurts
Starter cultures for sour droughts
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